Lack of Association of Serotonin 2A Receptor Gene in Japanese Patients with Obstructive Sleep Apnea Syndrome

نویسندگان

  • Kayoko Ikegawa
  • Masao Ota
  • Nobumitsu Kobayashi
  • Yunden Droma
  • Hironobu Yaegashi
  • Michiko Nishizawa
  • Masanori Yasuo
  • Kazuhisa Urushihata
  • Hiroshi Yamamoto
  • Masayuki Hanaoka
چکیده

Obstructive sleep apnea syndrome (OSAS) is char­ acterized by repeated partial or complete collapse of the pharynx during sleep, which results in apnea or hypopnea, associated with oxygen desaturation and arousal from sleep. OSAS is associated with meta­ bolic syndrome, cardiovascular diseases, and neu­ ropsychological sequelae. In addition, traffic and work-related accidents are frequently attributed to OSAS, which leads substantial social and economic costs. Clarifying the risk factors that confer suscep­ tibility to OSAS would contribute not only to the identification of diagnostic and prognostic biomark­ ers but also to the promotion of therapeutic and preventive strategies for individuals with a high risk of OSAS. In addition to the risk factors of age, Lack of Association of Serotonin 2A Receptor Gene in Japanese Patients with Obstructive Sleep Apnea Syndrome

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تاریخ انتشار 2017